منابع مشابه
Factor V Leiden, MTHFR C677T and Prothrombin Gene Mutation G20210A in Iranian Patients with Venous Thrombosis
Background: Factor V Leiden, Prothrombin gene (G20210A) and MTHFR (C677T) polymorphism are the main biomarkers for evaluation of tendency for venous thromboembolism. We aimed to investigate the frequency of mutations in factor V Leiden, Prothrombin G20210A and MTHFR C677T and identify the genetic status for these mutations in patients with venous thrombosis. Methods: This study was carried out...
متن کاملFactor V Leiden mutation and thromboembolism risk in women receiving adjuvant tamoxifen for breast cancer.
BACKGROUND Tamoxifen use has been associated with increased risk of thromboembolic events (TEs) in women with breast cancer and women at high risk for the disease. Factor V Leiden (FVL) is the most common inherited clotting factor mutation and also confers increased thrombosis risk. We investigated whether FVL was associated with TE risk in women with early-stage breast cancer who took adjuvant...
متن کاملFactor V Leiden mutation in pregnancy.
Normal maternal adaptation to pregnancy significantly increases the risk for thrombus formation. Inherited thrombophilias further increase risk for deep venous thrombosis and adverse outcome in pregnancy. Factor V Leiden mutation is the most common inherited thrombophilia, occurring in approximately 5% of the White and 1% of the Black populations. Nurses should be knowledgeable about screening ...
متن کاملFactor V Leiden Mutation Causing Thrombophilia
It has autosomal dominant inheritance and is the most common cause of inherited thrombophilia. FVL is the most prevalent thrombotic risk factor known in the Caucasian population (around 5%). [1] Heterozygotes have a three to five times increased risk of thrombosis. Homozygotes are much less common but have a much higher thrombotic risk, around eight times increased risk. It leads to a hypercoag...
متن کاملFactor V Leiden Mutation Causing Thrombophilia
It has autosomal dominant inheritance and is the most common cause of inherited thrombophilia. FVL is the most prevalent thrombotic risk factor known in the Caucasian population (around 5%). [1] Heterozygotes have a three to five times increased risk of thrombosis. Homozygotes are much less common but have a much higher thrombotic risk, around eight times increased risk. It leads to a hypercoag...
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ژورنال
عنوان ژورنال: JNCI Journal of the National Cancer Institute
سال: 2010
ISSN: 0027-8874,1460-2105
DOI: 10.1093/jnci/djq225